15 And I will put enmity between thee and the woman, and between thy seed and her seed; it shall bruise thy head, and thou shalt bruise his heel.
Commentary
This is a prophesy that was fulfilled by Jesus Christ’s Death on the Cross. The serpent her was under the influence of Satan and when Christ’s heel way wounded in crucifixion, He dealt Satan a fatal blow. 
This is known as the protoevangelion -- the "first gospel." It not only notes the "bruised heel" & "crushed head," but "her seed. " This indicates the virgin birth!
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